QABiology › What’s the difference between integral protein and peripheral protein?
Q

What’s the difference between integral protein and peripheral protein?

A

Integral proteins make up about 70% of the entire proteins found in cells. They are found in the phospholipid layer that surrounds every cell. Integral proteins are harder to separate from the bilayer because they bind themselves to the phospholipid layer of the cells. An example is rhodopsin.

When integral proteins are removed from the cell, the cell structure changes permanently. Another difference between integral protein vs peripheral protein is that peripheral proteins make up the remaining 30% of the proteins found in cell membranes. They can be found within or outside the phospholipid cell layer, and they are easier to remove than integral proteins. An example is cytochrome c.

3 years ago
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